High Levels of Serotonin - Health Dangers
5-hydroxytryptamine syndrome is an unfortunate as well as possibly fatal illness that afflicts hundreds of individuals around the world every year. The causes differ, however many cases of serotonin syndrome occur after prescription drugs react negatively with the human body. Doctors will usually refer to serotonin syndrome as serotonin toxicity, toxidrome, serotonin disorder, serotonin poisoning, hyperserotonemia, or perhaps even serotonergic syndrome due to the nature of the illness within the body. They insist that the excess serotonergic activity at the central nervous syndrome qualifies serotonin syndrome as a case of toxicity rather.
There tend to be a number of signs or symptoms that might indicate serotonin syndrome has affected your or an enjoyed one's body. They include: shivering, perspiration, agitation, temperature, fast heart rate, diarrhea, nausea, neuromuscular problems, and many notably, altered mental states. Typically these symptoms are noticeable inside 24 hours of taking the harmful drugs, or mixed dosages. A couple symptoms, however, tend to be noticeable inside only a very few minutes of ingesting the drugs. The many serious cases tend to be obvious through the drastic mental shock experienced by the body. The body temperature usually rises to as high as 106 degrees in numerous life-threatening cases. This temp causes the brain huge stress, which leads to a great altered state. In few cases abnormalities like rhabdomyolysis, seizures, and metabolic acidosis afflict the individual too. If you have any of these symptoms call an ambulance right away as serotonin syndrome, if left untreated, is a fatal disease. In order for you to avoid becoming sick you must avoid certain prescription drug combinations.
In 2007 the Food as well as Drug Management released reports warning headache sufferers to be wary of antidepressant treatments that might result in sickness. In fact, antidepressant medications are known to be one of the highest risk treatments. Fortunately, you are many likely definitely not at risk of serotonin syndrome if you take antidepressant medication alone. The use of tricyclic antidepressants for migraine headaches is typically done in small dosages just. In one recent study, 1700 different individuals were injected with sumatriptan in addition to an SSRI antidepressant (a common cause of 5-hydroxytryptamine problem) and there were no reported cases. These tend to be all positive signs.
The amount of serotonin syndrome sufferers is calculated at around 0.7 cases per 1000 months of SSRI antidepressant treatments. Additionally, there have been no cases reported from triptans alone. Therefore, it seems possible that the Food as well as Drug Management issued the caution thus that physicians will be made aware of the possibility of serotonin syndrome with these prescription drugs. If you're among the few individuals that have serotonin issue you need to be warned that there is no laboratory test for the disease. Diagnosis is done by analyzing the medical history, which is a slightly time intensive task for doctors. Also, doctors will test the Hunter Serotonin Toxicity Criteria to understand if serotonin syndrome is the correct diagnosis. Managing serotonin is done mainly be discontinuing the usage of disease inducing prescription drugs. At times people will elect to administer what tend to be called “serotonin antagonists”, such as cyproheptadine, that might additionally help resolve the problem.